Translating report proportions to incidence proportions

Putting an end to our search for the elusive underreporting factor

Summary

It is my intention to demonstrate how proportional reporting differences in post-approval pharmacovigilance databases like VAERS can be leveraged to establish the side effect profile of a drug.

Today I want to compare several types of adverse events’ incidence proportions found in literature with the report proportions in the VAERS database that i…